There’s only two ways that would happen:
1) Those stupid coven of Japanese goth-wannbe vamps got hold of the Scythe again, in which case, the world is supremely fucked, or 2) someone slipped me that lovely combination of drugs that Watchers used to give Slayers for their Cruciamentum.
And I would react by freaking the hell out. I might not always love my abilities, but I know what's out there. The world's full of monsters, and that I'm built to fight them and that I can protect myself and the people I love from them? Yeah, that's how I sleep at night, people.
So, yeah, it's safe to say, I would not be happy.